Yes. Standards like ASTM E1012 set limits on allowable misalignment, and if your machine exceeds those, any tests performed may be considered non-compliant. For example, in a NADCAP audit for materials testing, auditors will require evidence that your frame’s alignment is within acceptable limits. If you lack documentation or tools to prove this, it could result in a non-conformance. Poor alignment could also mean you’re inadvertently violating specifications of test standards (ASTM, ISO, DIN) that assume axial loading. In short, a misaligned machine can cause you to fail compliance checks and require corrective action.